Layer Blend Modes

Near the top of the palette there are blend mode options in the dropdown menu. This mode can be set for each individual layer, setting it apart from the Painting Mode in the Paint Buffer toolbar. The key difference is that where Painting Mode applies to the paint strokes that are baked down onto the model, the blend modes on the Layers palette apply to paint in the entire layer; not just what is baked.

Note:  If the blend mode applied to the layer affects the appearance of the overall stack, ensure that the layer is placed in the ideal order in the layer stack. If necessary, the layer can be moved after the blend mode has been set.